Drop Acid by David Perlmutter Summary
Overview of Drop Acid
Discover why uric acid is your body's hidden saboteur in "Drop Acid" - the book Harvard's Dr. Sinclair calls "life-changing." What if controlling this one molecule could prevent diabetes, heart disease, and brain fog? Melissa Urban's secret to vibrant health starts here.
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Key takeaways
The Hidden Metabolic Master Switch
Imagine a single molecule in your bloodstream secretly orchestrating the development of obesity, diabetes, heart disease, and even dementia. This isn't science fiction-it's the reality of uric acid, a metabolic byproduct that most doctors only associate with gout and kidney stones. Yet this overlooked compound may be the master regulator behind our most devastating modern diseases. For over a century, the medical establishment has largely ignored uric acid's broader impacts, despite pioneering work in the 1890s by Scottish physician Alexander Haig who connected it to conditions ranging from migraines to cardiovascular disease. Today, an estimated 70 million Americans have elevated uric acid levels-most without knowing it-putting them at significant risk for numerous health challenges. The optimal level appears to be 5.5 mg/dL or below, with each increase of 1 mg/dL above 7 mg/dL corresponding to an 8-13% higher death risk. What makes this discovery so significant is that uric acid comes from only three sources-fructose, alcohol, and purines-making it relatively straightforward to address through lifestyle changes.
Our Evolutionary Fat Switch
Fructose: The Sweet Saboteur
The Brain Under Siege
Beyond Diet: Hidden Uric Acid Triggers
The LUV Diet: Eating for Metabolic Health
Reclaiming Metabolic Health: Your Path Forward
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"BeFreed turned my commute into learning time. 20-min podcasts are perfect for finishing books I never had time for."
"BeFreed replaced my podcast queue. Imagine Spotify for books — that’s it. 🙌"
"It is great for me to learn something from the book without reading it."
"The themed book list podcasts help me connect ideas across authors—like a guided audio journey."
"Makes me feel smarter every time before going to work"
From Columbia University alumni built in San Francisco
"Instead of endless scrolling, I just hit play on BeFreed. It saves me so much time."
"I never knew where to start with nonfiction—BeFreed’s book lists turned into podcasts gave me a clear path."
"Perfect balance between learning and entertainment. Finished ‘Thinking, Fast and Slow’ on my commute this week."
"Crazy how much I learned while walking the dog. BeFreed = small habits → big gains."
"Reading used to feel like a chore. Now it’s just part of my lifestyle."
"Feels effortless compared to reading. I’ve finished 6 books this month already."
"BeFreed turned my guilty doomscrolling into something that feels productive and inspiring."
"BeFreed turned my commute into learning time. 20-min podcasts are perfect for finishing books I never had time for."
"BeFreed replaced my podcast queue. Imagine Spotify for books — that’s it. 🙌"
"It is great for me to learn something from the book without reading it."
"The themed book list podcasts help me connect ideas across authors—like a guided audio journey."
"Makes me feel smarter every time before going to work"
"Instead of endless scrolling, I just hit play on BeFreed. It saves me so much time."
"I never knew where to start with nonfiction—BeFreed’s book lists turned into podcasts gave me a clear path."
"Perfect balance between learning and entertainment. Finished ‘Thinking, Fast and Slow’ on my commute this week."
"Crazy how much I learned while walking the dog. BeFreed = small habits → big gains."
"Reading used to feel like a chore. Now it’s just part of my lifestyle."
"Feels effortless compared to reading. I’ve finished 6 books this month already."
"BeFreed turned my guilty doomscrolling into something that feels productive and inspiring."
"BeFreed turned my commute into learning time. 20-min podcasts are perfect for finishing books I never had time for."
"BeFreed replaced my podcast queue. Imagine Spotify for books — that’s it. 🙌"
"It is great for me to learn something from the book without reading it."
"The themed book list podcasts help me connect ideas across authors—like a guided audio journey."
"Makes me feel smarter every time before going to work"
"Instead of endless scrolling, I just hit play on BeFreed. It saves me so much time."
"I never knew where to start with nonfiction—BeFreed’s book lists turned into podcasts gave me a clear path."
"Perfect balance between learning and entertainment. Finished ‘Thinking, Fast and Slow’ on my commute this week."
"Crazy how much I learned while walking the dog. BeFreed = small habits → big gains."
"Reading used to feel like a chore. Now it’s just part of my lifestyle."
"Feels effortless compared to reading. I’ve finished 6 books this month already."
"BeFreed turned my guilty doomscrolling into something that feels productive and inspiring."
"BeFreed turned my commute into learning time. 20-min podcasts are perfect for finishing books I never had time for."
"BeFreed replaced my podcast queue. Imagine Spotify for books — that’s it. 🙌"
"It is great for me to learn something from the book without reading it."
"The themed book list podcasts help me connect ideas across authors—like a guided audio journey."
"Makes me feel smarter every time before going to work"
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